Statistical Evidence in Medical Trials
Oxford University Press | May 4, 2006 | ISBN-10: 0198567618 | 216 pages

Statistical Evidence in Medical Trials is a lucid, well-written and entertaining text that addresses common pitfalls in evaluating medical research. Including extensive use of publications from the medical literature and a non-technical account of how to appraise the quality of evidence presented in these publications, this book is ideal for health care professionals, students in medical or nursing schools, researchers and students in statistics, and anyone needing to assess the evidence published in medical journals.

Victor R. Preedy, Ronald R. Watson
"Handbook of Disease Burdens and Quality of Life Measures"
Springer | 2009 | ISBN: 0387786643 | 4448 pages

The impact of illness on individual lives and society at large was once considered too vast to gauge. More recently, quantitative measures of quality of life, life expectancy, and the financial costs of illness and treatment are showing not only how this impact can be calculated but also how the results can be used to further research and improve public health. The Handbook of Disease Burdens and Quality of Life Measures is the first comprehensive reference to these instruments and their findings on an international scale.

The Handbook features in-depth reviews of disability-adjusted life years (DALYs), quality-adjusted life years (QALYs), quality of life and financial measures for over 120 diseases and conditions. Its editors have organized this critical information for maximum access and ease of use, with abstracts, definitions of key terms, summary points, and dozens of figures and tables that can enhance the text or stand alone. Readers may access data by country, region, or population, or by disease entity, e.g.:


Cardiovascular and pulmonary, including hypertension, stroke, and COPD.


Viral, bacterial, microbial, parasitic, and other infectious diseases, including HIV/AIDS, tuberculosis, encephalitis, and dengue fever, plus vaccination issues.


Cancer, including breast, prostate, cervical, colorectal, and pediatric.


Psychosocial, psychiatric, sensory, and addictive (drugs, alcohol, tobacco) disorders.


Topics ranging from toxic exposure (injection contamination, occupational hazards, environmental pollutants), to special populations (children, the elderly in China, the city of Los Angeles), to commonly-occurring conditions (rheumatoid arthritis, menopause, macular degeneration).


Plus chapters discuss specific measures for assessing health and disease impact, such as the WHOQoL questionnaire, the SF-36 Short-Form Health Survey, and the Quality of Life in Later Life Questionnaire.

The Handbook’s broad coverage and meticulous, up-to-date detail make it essential for public health researchers in the area of quality of life.

Joseph Tal

"Strategy and Statistics in Clinical Trials: A Non-Statisticians Guide to Thinking, Designing and Executing"
English | 2011 | ISBN : 0123869099 | 288 pages

Strategy and Statistics in Clinical Trials is for all individuals engaged in clinical research, including professors, physicians, researchers in corporate and government laboratories, nurses, members of the allied health professions, and post-doctoral and graduate students who are potentially less exposed to understanding the pivotal role of statistics.

Enables nonstatisticians to better understand research processes and statistics' role in these processes . Offers real-life case studies and provides a practical, "how to" guide to biomedical R&D . Delineates the statistical building blocks and concepts of clinical trials . Promotes effective cooperation between statisticians and important other parties.

Ton J. Cleophas, Aeilko H. Zwinderman
"Statistics Applied to Clinical Studies, 5th Edition"
Sp nger | 2012 | ISBN: 940072862X | 778 pages

Thanks to the omnipresent computer, current statistics can include data files of many thousands of values, and can perform any exploratory analysis in less than seconds. This development, however fascinating, generally does not lead to simple results. We should not forget that clinical studies are, mostly, for confirming prior hypotheses based on sound arguments, and the simplest tests provide the best power and are adequate for such studies. In the past few years the authors of this 5th edition, as teachers and research supervisors in academic and top-clinical facilities, have been able to closely observe the latest developments in the field of clinical data analysis, and they have been able to assess their performance. In this 5th edition the 47 chapters of the previous edition have been maintained and upgraded according to the current state of the art, and 20 novel chapters have been added after strict selection of the most valuable and promising novel methods. The novel methods are explained using practical examples and step-by-step analyses readily accessible for non-mathematicians. All of the novel chapters have been internationally published by the authors in peer-reviewed journal, including the American Journal of Therapeutics, the European Journal of Clinical Investigation, The International journal of Clinical Pharmacology and therapeutics, and other journals, and permission is granted by all of them to use this material in the current book. We should add that the authors are well-qualified in their fields of knowledge. Professor Zwinderman is president-elect of the International Society of Biostatistics, and Professor Cleophas is past-president of the American College of Angiology. From their expertise they should be able to make adequate selections of modern methods for clinical data analysis for the benefit of physicians, students, and investigators. The authors, although from a different discipline, one clinician and one statistician, have been working and publishing together for over 10 years, and their research of statistical methodology can be characterized as a continued effort to demonstrate that statistics is not mathematics but rather a discipline at the interface of biology and mathematics. They firmly believe that any reader can benefit from this clinical approach to statistical data analysis.

Statistical Bioinformatics: with R by Sunil Mathur
Publisher: Academic Press; 1 edition (January 26, 2010) | ISBN: 0123751047 | Pages: 336

Designed for a one or two semester senior undergraduate or graduate bioinformatics course, Statistical Bioinformatics takes a broad view of the subject - not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications. The inclusion of R code as well as the development of advanced methodology such as Bayesian and Markov models provides students with the important foundation needed to conduct bioinformatics.

Paul Glasziou, Chris Del Mar, Janet Salisbury
Evidence-Based Practice Workbook (2nd edition)
Published: 2007-09-04 | ISBN: 1405167289 | 208 pages

The Evidence-based Practice Workbook is an ideal tool for use by GPs, medical specialists and other healthcare professionals to learn the concepts of evidence-based practice (EBP). Practical and interactive, this workbook provides simple methods to help health professionals find and use the best evidence to answer clinical questions, developing their skills in:
asking clinical questions
searching for answers
discriminating good from poor information and research
using the answers to make clinical decisions.
This attractive, colour workbook provides a clear explanation of EBP skills and concepts. Written by internationally respected authors, this expanded and updated edition has been developed from evidence-based practice workshops run by the Centre for Evidence-Based Medicine at the University of Queensland and Oxford, and contains information and exercises to help health professionals learn how to use EBP in their clinical practice.

David Bowers, Allan House, David Owens
Understanding Clinical Papers (2nd edition)
Published: 2006-06-26 | ISBN: 0470091304 |  244 pages

Now in its Second Edition, this book helps to unravel the process of evidence-based practice, which requires clinicians to evaluate and collate information from the journals they read. Understanding Clinical Papers, Second Edition uses actual papers to illustrate how to understand and evaluate published research, but goes beyond this to provide an explanation of a range of important research-related topics.
Understanding Clinical Papers, Second Edition:
Covers everything necessary to understand a clinical research paper
Examples are illustrated and based uniquely on tables, abstracts and exerts from published clinical research papers
Amazingly clear, lively, accessible style
The new edition has been markedly improved and extended, containing, for example, new material on measurement scales, systematic reviews, writing a paper, statistics software and critical appraisal
Understanding Clinical Papers, Second Edition is an invaluable resource for everyone involved directly or indirectly in health care – an ultimate guide for those who read clinical literature.

Michael J. Campbell, David Machin, Stephen J. Walters

"Medical Statistics: A Textbook for the Health Sciences, 4th Edition"
English | 2007 | ISBN: 0470025190 | 344 pages

Provides students and practitioners with a clear, concise introduction to the statistics they will come across in their regular reading of clinical papers.
Written by three experts with wide teaching and consulting experience, Medical Statistics: A Textbook for the Health Sciences, Fourth Edition:

-Assumes no prior knowledge of statistics
-Covers all essential statistical methods
-Completely revised, updated and expanded
-Includes numerous examples and exercises on the interpretation of the statistics in papers published in medical journals

Sinead Keeney, Hugh McKenna, Felicity Hasson

"The Delphi Technique in Nursing and Health Research"
English | 2011-02-02 | ISBN: 1405187549 | 208 pages

The Delphi Technique in Nursing and Health Research is a practical guide to using the Delphi methodology for students and researchers in nursing and health. It adopts a logical step-by-step approach, introducing the researcher to the 'Delphi', outlining its development, analysing key characteristics and parameters for the successful application of the Delphi and exploring its applications in nursing and health. The book addresses issues of methodology, design, framing the research question, sampling, instrumentation, methodological rigour, reliability and validity, and methods of data analysis.
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