Dominik T. Schneider, Ines B. Brecht Rare Tumors In Children and Adolescents" ISBN: 3642041965 2012 557 pages This is the first book to be devoted exclusively to rare tumors in children and adolescents, and its aim is to provide up-to-date information on their diagnosis and clinical management. The opening section addresses general issues including epidemiology, risk factors/etiology, biology and genetics, early detection, and screening. It also discusses solutions to assist in the management of rare tumors, such as international networking and internet platforms. In the second section, specific malignancies are described, with practical guidance on diagnostic workup, multimodal therapy, follow-up, and adverse effects. Discussion of differential diagnosis encompasses both frequent and rare tumor types, which should enable the clinician to take rare entities into account during the diagnostic assessment. Each chapter goes on to provide detailed therapeutic guidelines for specific rare tumors. The authors are a multidisciplinary group of specialists who have dedicated themselves to this group of tumors.
Primo N. Lara Jr., Eric Jonasch Kidney Cancer: Principles and Practice Published: 2012-03-13 | ISBN: 3642218571 | 309 pages This interdisciplinary textbook encompasses all clinically relevant aspects of the disease and is designed to be as user-friendly as possible in order to meet the needs of the busy practitioner. To this end, the informative text is complemented by helpful boxed sections that present essential ‘take home’ points and illustrative patient-oriented cases. Original high-quality images, some in color, are included whenever necessary to simplify particularly complex material. The authors are an international group of acknowledged experts in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others. This clinically oriented volume will be of great interest to clinicians, researchers, residents, and fellows, as well as to students and knowledgeable lay people.
The Surgery of Childhood Tumors Springer | April 10, 2008 | ISBN-10: 3540297332 | 626 pages
Beginning with the scientific basis of tumors, "The Surgery of Childhood Tumors" provides up-to-date information on epidemiology, cytogenetics and molecular biology, before looking at current treatments, integrating surgery, neoadjuvant and adjuvant chemotherapy and radiation therapy. Additionally, a chapter on counseling reflects the book's holistic approach to treating children with cancer.
The chapters are written by world-renowned international authorities on pediatric cancer from major children's cancer groups in the UK, Europe and the US. Contributors discuss geographical variations in treatment for each type of tumor. Excellent full-colour pictures and detailed line drawings illustrate all aspects of managing childhood tumors, including technical details of operation which are often neglected in other texts. This comprehensive book provides a contemporary approach for pediatric, general and urological surgeons dealing with childhood tumors. New chapters in this second edition provide the latest developments and strategies in pediatric surgical oncology.
Despite the tremendous strides that have been made in developing successful therapies for many pediatric cancers, certain types of brain tumors still strike terror in the minds of parents, patients, and physicians. Pediatric CNS Tumors offers a concise account of the various histologic types of brain tumors in children and provides clear descriptions of current management and leading-edge technology. The book is written at a level of sophistication that will make it useful to physicians who are directly involved in the care of children with tumors of the central nervous system. Yet it will also be of interest to a broader audience, because it integrates information from a wide array of subspecialties that contribute to the optimal care of a child with a brain tumor. Because the tumors that arise in the developing brain are markedly different from tumors in adults and principally involve primary rather than metastatic disease, this book fills a niche. A helpful feature, mentioned by the editors, is the roster of authors, who are affiliated mainly with a single institution, at the University of California, San Francisco. Rather than leading to provincialism, this structure makes possible the presentation of a coherent philosophy regarding complex management decisions. In most institutions, decisions about treatment for pediatric patients with brain tumors require coordinated input from several disciplines, and such an approach is evident in the organization and content of this book. That said, in some instances, the treatment strategies presented may differ slightly from practices at other institutions and, as with any complex and evolving area of medicine, should be interpreted with some flexibility. For the most part, the book's chapters are devoted to the major histologic types of pediatric tumors of the central nervous system and include sections on epidemiology, pathology, imaging, and therapy. This scheme leads to some degree of repetition in chapters that discuss gliomas but focus on four anatomical compartments. However, there is merit to organizing the chapters in such a manner, because, for example, the biology of brainstem gliomas differs considerably from that of cerebellar astrocytomas, as do therapies for the two types of tumors. The format also increases the stand-alone usefulness of various chapters as reference sources. The final 4 chapters address imaging, surgery, chemotherapy, and radiation therapy in a more comprehensive manner than do the 11 chapters on various types of tumors. Since many pediatric patients with brain tumors are enrolled in cooperative-group clinical trials, a description of the design and results of previous research studies is presented in individual chapters. This provides an important historical perspective. Two aspects of the care of pediatric patients should have received more comprehensive treatment in this book. The first is management of long-term follow-up care of survivors. As might be imagined, the tumor itself, as well as surgery, radiation therapy, and chemotherapy, can have important effects on the developing brain and pose lifelong sequelae. A multidisciplinary approach to optimizing the health and function of survivors is considered a key component of therapy at many medical centers. A description of the organization of a comprehensive brain-tumor clinic and the approach to long-term care would benefit many readers. The second aspect relates to the ineffectiveness of treatment for several types of newly diagnosed and recurrent brain tumors. Palliative care has a critical role in the treatment of patients not only with terminal illnesses, but also with potentially life-threatening diseases. Perhaps more important, such an approach can help guide families along a sometimes long and difficult road. Thus, it is realistic to consider pediatric palliative medicine as an important component of the management of such cases. These criticisms aside, this up-to-date book, which includes some of the exciting recent advances in the molecular pathology of pediatric brain tumors, is well organized and offers a unified and comprehensive reference beyond what can be found in textbooks. It will be useful for practitioners in a broad cross section of medical specialties that intersect in this fascinating yet sometimes devastating type of cancer.
Nicholas C. Gourtsoyiannis, Pablo R. Ros Radiologic-Pathologic Correlations from Head to Toe: Understanding the Manifestations of Disease Published: 2005-06-08 | ISBN: 3540043950 | 764 pages
This book, first of its kind and written by leading experts, offers a comprehensive review of imaging of the whole body based on correlating the radiologic findings with gross and microscopic pathology . Taking advantage of all imaging modalities, the authors give detailed descriptions of radiologic presentations with pathologic correlation, of a broad spectrum of diseases from most organ systems, including the nervous system, head and neck, chest, gastrointestinal and urogenital system, musculoskeletal system and breast. The book helps the clinician to apply the principles of radiologic-pathologic correlation to the interpretation of radiologic studies and therefore to better understand the clinical and pathologic implications of the radiologic appearance. Furthermore this radiologic-pathologic correlation allows to refine the differential diagnosis in key disease entities of the main organ systems. The book is richly illustrated with high-resolution images, many of them in color, and will serve as a unique source of information for radiologists, gastroenterologists, gastrointestinal surgeons, pathologists, gynecologists, urologists and oncologists.
Naoto T. Ueno, Massimo Cristofanilli Inflammatory Breast Cancer: An Update Published: 2012-03-31 | ISBN: 9400739060 | 300 pages
Inflammatory breast cancer is the most deadly subtype of breast cancer because it can spread to other organs despite of multidisciplinary approach. However, the molecular characteristic of this aggressive disease is yet to be established. This book is the one of the few textbooks that summarizes the latest information dated to inflammatory breast cancer. The uniqueness of this book is that it has summarized the latest molecular and mechanistic findings, which may lead to novel diagnostic tool or therapeutic approach to fight this deadly disease.
With thorough updates throughout, Clinical Radiation Oncology provides the most comprehensive, authoritative, and up-to-date information available for treating patients with cancer. From a multidisciplinary perspective, this new edition, edited by Drs. Leonard L. Gunderson and Joel E. Tepper, examines the therapeutic management of specific disease sites based on both single-modality and combined-modality approaches - providing you with the well-rounded, cutting-edge guidance you need to offer the most effective treatments. A consistent chapter format, full-color design, and access to the full text at www.expertconsult.com make reference fast and easy. It is an ideal resource for mastering the latest, most effective techniques and modalities! Deepen your knowledge with a comprehensive, clinical approach to the scientific foundations of radiation oncology and general oncology as well as state-of-the-art techniques and modalities.
Implement a multidisciplinary, "team care" approach to providing intricate treatment plans for patients, often in conjunction with medical oncologists, and surgeons.
Broaden your understanding of the basic biology of the disease processes.
Examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches.
Quickly and easily find critical information thanks to an easily accessible, full-color design with over 800 color figures that clearly depict treatment techniques. Get broad multimodality perspectives and unique insights from a diverse team of respected editors and contributors -many of whom are new to this edition - affiliated with institutions across North America and internationally
Access the fully searchable text anywhere, anytime at www.expertconsult.com, along with references, additional images and tables, video clips and more!
Stay current with comprehensive updates throughout that include a new chapter on survivorship issues, and additional video clips on treatments such as prostate and penile cancer brachytherapy.
Improve outcomes by providing the most effective treatment for each patient with expanded coverage of new modalities and treatment regimens.
Understand and comply with the latest staging guidelines.
Drs. Gunderson and Tepper give you quick access to all the clinical tools you need to master the newest techniques and modalities in radiation oncology.
Boris R. Minev Cancer Management in Man: Chemotherapy, Biological Therapy, Hyperthermia and Supporting Measures Published: 2011-01-13 | ISBN: 9048197031 | 540 pages
This book represents a comprehensive description and evaluation of the most up-to-date approaches to cancer management. Each chapter, prepared by leading basic researchers and clinicians, provides an in depth description of a specific method for cancer management. The chemotherapy section of the book is updated to include the newest drugs as well as those currently in development. Organized by drug class, this section provides the latest information on most drugs, including their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The biological therapy section of the book provides expanded coverage of the currently used cytokines, vaccines, and cell based therapies of cancer. Full consideration is also given to other modern treatment approaches, such as tyrosine kinase inhibitors, inhibitors of tumor angiogenesis, and the transcatheter management of cancer. Current advances in hyperthermia in cancer treatment, hematologic and nutritional support, bone marrow transplantation, pain management and care of the terminally ill patients with cancer are also presented. In summary, this book provides a comprehensive coverage of the current knowledge on the most innovative, systematic and multidisciplinary approaches to the treatment of patients with cancer.
J. Michael Dixon "ABC of Breast Diseases" English | 2006 | ISBN: 0727918281 | 120 pages |
Covers all the recent advances in screening, helping with the assessment of symptoms, prognosis and treatments of breast diseases
Breast diseases are becoming more and more common and health professionals in almost every field will probably come into contact with a patient who has a breast disorder. This third edition provides an account of the current knowledge on benign and malignant breast conditions and the treatment of them.
It covers all the recent advances in screening and adjuvant treatment, including the new aromatase inhibitor clinical trials and improvements in metastatic disease treatment. New chapters on prognosis and clinical trials have also been added.
Edited and written by experts in the field, this book appeals to a wide readership including general practitioners, practice nurses, breast care nurses, surgeons or oncologists in training, and medical students. It contains such a wealth of knowledge it will also be a valuable source of information for established breast surgeons and oncologists.
Michael J. Murphy - Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma Published: 2011-12-01 | ISBN: 1607614324 | 336 pages
This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers.
Katrin Scheinemann, Allison E. Boyce - Emergencies in Pediatric Oncology Published: 2011-12-02 | ISBN: 1461411734 | 196 pages
Pediatric oncology is a considerably complex discipline requiring frequent need for reference material. Emergencies in Pediatric Oncology meets this objective by serving as a concise, practical resource for the hurried physician. Replete with diagrams and written in a clear, succinct style, this title offers an easy-to-read guide especially useful for residents, fellows, and nurses. Providing an overview of the epidemiology of childhood cancer and the history of its treatment, this title also addresses a range of key problems in the pediatric oncologic setting, covering the most common emergencies and providing short, practical guidelines on how to handle them. Written by authorities from an array of disciplines, this helpful resource provides answers and concrete guidance and is a valuable contribution to the literature in pediatric oncology.
Peter Mueller, Andreas Adam - Interventional Oncology: A Practical Guide for the Interventional Radiologist Published: 2011-11-24 | ISBN: 1441914684 | 200 pages
Interventional Oncology is a fast-growing new field, as well as an emerging specialty. Many minimally-invasive, imaging-guided procedures seem set to replace more traditional open surgical techniques of treating solid tumors in a variety of organs. The aim of this book is to describe new interventional radiological methods in a succinct and practical form. Diagnostic radiological considerations relevant to the selection and follow-up of patients are also covered. The book begins with an overview of the basic principles of current interventional techniques, including thermal ablation, high intensity focused ultrasound, and embolization. Later chapters focus on tumors of the liver, kidney, lung, and bone, placing new interventional techniques in context by referring to the surgical and oncologic methods of treating the same conditions. With an emphasis on best practices, Interventional Oncology: A Practical Guide for the Interventional Radiologist will serve as a definitive guide to practicing physicians involved in this rapidly evolving field.
This book can enlighten important issues involved in the management of cancer, summarizing the state-of-the-art knowledge regarding the disease control and treatment; thus, providing means to improve the overall care of patients that daily battle against this potentially lethal condition.
This issue is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field.
Contents Section 1 Cancer Treatment: Conventional and Innovative Pharmacological Approaches 1 Conventional Cancer Treatment 2 Target Cancer Therapy 3 Anticancer Properties of Cardiac Glycosides 4 Liposomes as Carriers of Anticancer Drugs Section 2 Combinatorial Strategies to Fight Cancer: Surgery, Radiotherpay, Backytherapy, Chemotherapy, and Hyperthermia 5 The Role of Surgery in the Treatment of Hepatocellular Carcinoma 6 Laparoscopic Surgery in Genitourinary Cancer Treatment 7 Current Strategies in the Management of Adenocarcinoma of the Rectum 8 Mesothelioma: An Evidence-Based Review 9 Definitive Chemo-Radiotherapy for Resectable Esophageal Cancer — Unresolved Problems Remain 10 A Review of Radiation Therapy's Role in Early-Stage Breast Cancer and an Introduction to Electronic Brachytherapy 11 Radiosurgery and Hypofractionated Stereotactic Irradiation with Photons or Protons for Tumours of the Skull Base 12 Hyperthermia: Cancer Treatment and Beyond 13 Glioblastomas, Astrocytomas: Survival Amelioration Adding Hyperthermia to Conformal Radiotherapy and Temozolomide — Use of Pegylated Doxorubicin and Hyperthermia in the Treatment of a Recurrent Case Section 3 The Immunotherapy of Cancer 14 Targeted Cancer Therapy bv Dendritic Cell Vaccine 15 Immunotherapy of Urinary Bladder Carcinoma: BCG and Beyond 16 Anti-Angiogenic Active Immunotherapy for Cancers: Dawn of a New Era? Section 4 Multidisciplinarity in Cancer Therapy: Nutrition and Beyond 17 Nutrigenomics and Cancer Prevention 18 The Impact of Vitamin D in Cancer 19 The Treatment of Cancer: A Comprehensive Therapeutic Model Entailing a Complex of Interaction Modalities Section 5 Supportive Care for Cancer Patients 20 Supportive and Palliative Care in Solid Cancer Patients 21 Impact of Cancer Treatment on Reproductive Health and Options for Fertility Preservation Section 6 Perspectives in Cancer Biology and Modeling 22 Sialyl Salivary-Type Amylase Associated with Ovarian Cancer 23 Role of CREB Protein Family Members in Human Haematological Malignancies 24 Life-Cycling of Cancer: New Concept
The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public and for patients who might want to learn about this treatment option.
Liver metastases are a frequent and often fatal occurrence in cancer patients, particularly those with malignancies of the gastrointestinal (GI) tract. While recent improvements in surgical techniques and a more aggressive approach to resection of liver metastases have improved long term survival for some patients, most patients with hepatic metastases still succumb to their disease.
"Frontiers in Radiation Oncology" ed. by Tejinder Kataria InTeOpP | 2013 | ISBN: 9535111634 9789535111634 | 224 pages
The book is meant for physicians, physicists, dosimetrists and counselors who are trying to provide a holistic care in cancer while trying to understand the complex basics of radiation interaction within the human body.
Contents Preface Section 1 Molecular Biology of Radiation Therapy 1 Histone Acetyltransferases (HATs) Involved in Non-Homologous End Joining as a Target for Radiosensitization 2 A Framework for Modeling the Cellular Defending Mechanisms Against Genome Stress Under Radiotherapy Section 2 Dosimetry and Medical Physics 3 Applications to Radiotherapy Using Three Different Dosimetric Tools: MAGIC-f Gel, PENELOPE Simulation Code and Treatment Planning System 4 3D Dosimetric Tools in Radiotherapy for Photon Beams 5 A Respiratory Motion Prediction Based on Time-Variant Seasonal Autoregressive Model for Real-Time Image-Guided Radiotherapy 6 Neutron Dose Equivalent in Tissue Due to Linacs of Clinical Use Section 3 Clinical Radiotherapy 7 Curative Radiotherapy in Metastatic Disease: Howto Develop the Role of Radiotherapy from Local to Metastases 8 Locally Advanced Esophageal Cancer 9 Reduction Mammaplasty and Intra-Operative Radiotherapy (IORT) in Conservative Surgery 10 Effects of Radiotherapy on Pharyngeal Reconstruction After Pharyngo-Laryngectomy Section 4 Quality of Life Issues 11 Breast Cancer Post Treatment Quality of Life 12 Nutrition Intervention Improves Nutritional Status and Quality of Life Outcomes in Patients Undergoing Radiotherapy
Stephen Lutz, Edward Chow "Radiation Oncology in Palliative Cancer Care" 2013 | ISBN-10: 1118484150 | 400 pages
Palliative Medicine is the professional medical practice of prevention and relief of suffering and the support of the best possible quality of life for patients and their families, regardless of the stage of the disease or the need for other therapies. The most common cause for palliative care referral is terminal cancer, and a large proportion of those referrals include patients who will need palliative radiotherapy during the course of their disease. Still, there are barriers to coordinated care between radiation oncologists and palliative care physicians that differ fr om one country to another. Until now, one overarching lim itation to appropriate concurrent care between the specialties across all countries has been the lack of a comprehensive yet concise reference resource that educates each of the specialties about the potential synergistic effects of their cooperation. This book fills that void.
Radiation Oncology in Palliative Cancer Care: Is the first book-length treatment of this important topic available on the market Is authored by world-renowned experts in radiation oncology and palliative medicine Uses a multidisciplinary approach to content and patient treatment Features decision trees for palliative radiotherapy based upon factors such as patient performance status and prognosis Pays careful attention to current best practices and controversies in the delivery of end-of-life cancer care
This book is an important resource for practicing radiation oncologists and radiation oncologists in training, as well as hospice and palliative medicine physicians and nurses, medical oncologists, and geriatricians.
Breast Cancer Epidemiology Springer | 2010 | ISBN: 1441906843 | 417 pages
Breast cancer remains a disease of considerable public health importance worldwide, with over 800,000 new cases diagnosed globally each year. Considerable energy is currently being spent by researchers to further our understanding of this complex disease, however, keeping up with all of the new data is a real challenge given the sheer volume of information that becomes available on a daily basis. The purpose of this book would be to provide a comprehensive review of breast cancer epidemiology, covering the topics of disease burden, etiology, risk factors, prevention, early detection/screening, treatment, and outcomes.
George R. Blumenschein, "Quest for the Cure: Reflections on the Evolution of Breast Cancer Treatment" English | ISBN: 0124201539 | 2013 | 108 pages
This original fourteen chapter book is a brief, slightly autobiographic tale of medical oncologists, surgeons, radiation oncologists, and breast cancer patients in a well-established cancer center in Texas, who pursued the goal of cure for breast cancer. The evolution of improved outcomes in the treatment of microscopic metastatic breast cancer is also the story of the development of adjuvant chemotherapy for post-operative breast disease. The adjuvant therapy of breast cancer came about with the realization that this malignancy, when diagnosed in most patients, had spread beyond the confines of the primary cancer. Patient histories in the form of Case Studies are used to illustrate certain issues. It is devoted to the development of the chemotherapeutic regimens that currently are used to treat patients with advanced breast cancer.