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Неврология, Нейрохирургия, детская и взрослая

"Neurodegenerative Diseases" ed. by Uday Kishore
InTeOpP | 2013 | ISBN: 9535110880 9789535110880 | 637 pages |

This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. Novel approaches to therapeutic interventions have also been presented. It is hoped that students, scientists and clinicians shall find this very informative book immensely useful and thought-provoking.

The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases and secretase, regulators, cholesterol, zinc, microglia, astrocytes, oligodendrocytes, etc, have been discussed in the context of disease progression.

Section 1 Disease Mechanisms in Alzheimer's Disease
1 Alzheimer's Disease: A Clinical Perspective
2 Late-Onset Alzheimer's Disease: Risk Factors, Clinical Diagnosis and the Search for Bio markers
3 Role of Protein Aggregation in Neurodegenerative Diseases
4 Role of Oxidative Stress in A|3 Animal Model of Alzheimer's Disease: Vicious Circle of Apoptosis, Nitric Oxide and Age
5 Alterations of Mitochondria and Golgi Apparatus Are Related to Synaptic Pathology in Alzheimer's Disease
6 Caspases in Alzheimer's Disease
7 Brain Reserve Regulators in Alzheimer's Disease
8 Cholesterol and Alzheimer's Disease
Section 2 Therapeutic Aspects of Alzheimer
9 Emerging Therapeutic Strategies in Alzheimer's Disease
10 Dropping the BACE: Beta Secretase (BACEl) as an Alzheimer's Disease Intervention Target
11 QSAR Analysis of Purine-Type and Propafenone-Type Substrates of P-Glycoprotein Targeting p-Amyloid Clearance
12 Therapeutic Interventions in Alzheimer Disease
Section 3 Pathopysiological Aspects of Other Neurodegenerative Diseases
13 Other Dementias
14 The Role of Epigenetics in Neurodegenerative Diseases
15 Plasma Membrane Channels Formed by Connexins or Pannexins in Microglia: Possible Role in the Inflamed Brain
16 Influence of Obesity on Neurodegenerative Diseases
17 Electro-Physiological Approaches to Monitoring Neuro-Degenerative Diseases
18 Oxidative Changes and Possible Effects of Polymorphism of Antioxidant Enzymes in Neurodegenerative Disease
19 Intermediate Filaments in Neurodegenerative Diseases
20 Astrocytes Role in Parkinson: A Double-Edged Sword
21 Zinc and Neurodegenerative Diseases
22 Oligodendrocyte Metabolic Stress in Neurodegeneration
Section 4 Miscellaneous
23 Spinal Muscular Atrophy: Classification, Diagnosis, Background, Molecular Mechanism and Development of Therapeutics
24 Pharmacological Treatment of Acute Ischemic Stroke
25 Cognitive Dysfunction Syndrome in Senior Dogs

Pauline M. Pope, Severe and Complex Neurological Disability: Management of the Physical Condition
ISBN: 0750688254 | edition 2007 | 286 pages

This book presents a holistic approach to the complete, long-term, day-to-day care of patients disabled by neurological conditions, emphasizing practices that promote physical well-being and minimize secondary complications. It focuses on physical management within the context of the lifestyle of the disabled person and primary caregiver. In addition, it highlights the difficulties commonly encountered when implementing a physical management regime, and discusses the importance of compromise.

Jennifer Niskala Apps, Kevin D. Walter - Pediatric and Adolescent Concussion: Diagnosis, Management, and Outcomes
Published: 2011-12-14 | ISBN: 0387895442 | 227 pages

Between the growing numbers of children and adolescents playing sports and the increased attention to head injuries by the larger sports community and the general public, pediatric concussions are emerging as a major concern. And as practitioners are seeing more young clients with head injuries, questions arise about age-appropriate assessment, diagnosis, treatment, and return to activity. Pediatric and Adolescent Concussion: Diagnosis, Management, and Outcomes offers evidence-based guidelines where few previously existed. This comprehensive volume clearly explains the effects of traumatic injury on the developing brain in sports- and non-sports-related contexts, and establishes a framework for immediate and long-term management, especially the crucial first 24 hours. Chapters provide a basic grounding in its subject with a history of concussion as a medical entity and a review of definitional and classification issues, take the reader through the steps of a neuropsychological evaluation, pinpoint post-injury issues, and offer strategies for the prevention of further or future injury. Pediatric and Adolescent Concussion: Diagnosis, Management, and Outcomes serves as both educational resource and practical framework for a wide array of professionals, including neuropsychologists, sports medicine physicians, child psychologists and psychiatrists, pediatric and family physicians, athletic trainers, social workers, and educators.

Andrew D. Norden, "Primary Central Nervous System Tumors: Pathogenesis and Therapy (Current Clinical Oncology) "
Publisher: Hu...na Press | ISBN: 1607611651 | 2011 | 583 pages

This comprehensive, yet practical, text is a ready collection of the most up-to-date information on primary CNS tumors. Authored by a carefully selected group of the world’s leading clinicians and scientists, the book is divided into three sections. The opening chapters cover general principles, including epidemiology, pathogenesis, tumor stem cells, supportive care, complications of therapy, and quality of life. The remaining two sections are comprised of treatment-oriented chapters covering the spectrum of gliomas and rarer tumor types. Each of these chapters presents multi-disciplinary therapeutic approaches and addresses specific disease concerns. Throughout, the authors incorporate the cutting-edge advances in molecular biology and genomics that are revolutionizing neuro-oncology. The result is an important clinical resource which provides evidence-based data and interpretation essential to intelligent therapeutic decision making.

H. Richard Winn MD, "Youmans Neurological Surgery, 4-Volume Set: Expert Consult - Online and Print, 6e"
English | 2011 | ISBN: 1416053166 | 4960 pages

Effectively perform today's most state-of-the-art neurosurgical procedures with Youmans Neurological Surgery, 6th Edition, edited by H. Richard Winn, MD. Still the cornerstone of unquestioned guidance on surgery of the nervous system, the new edition updates you on the most exciting developments in this ever-changing field. In print and online, it provides all the cutting-edge details you need to know about functional and restorative neurosurgery (FRN)/deep brain stimulation (DBS), stem cell biology, radiological and nuclear imaging, neuro-oncology, and much more.

And with nearly 100 intraoperative videos online at www. expertconsult .com, as well as thousands of full-color illustrations, this comprehensive, multimedia, 4-volume set remains the clinical neurosurgery reference you need to manage and avoid complications, overcome challenges, and maximize patient outcomes.

• Overcome any clinical challenge with this comprehensive and up-to-date neurosurgical reference, and ensure the best outcomes for your patients.
• Rely on this single source for convenient access to the definitive answers you need in your practice.
• Successfully perform functional and restorative neurosurgery (FRN) with expert guidance on the diagnostic aspects, medical therapy, and cutting-edge approaches shown effective in the treatment of tremor, Parkinson's disease, dystonia, and psychiatric disorders.
• Sharpen your neurosurgical expertise with updated and enhanced coverage of complication avoidance and intracranial pressure monitoring, epilepsy, neuro-oncology, pain, peripheral nerve surgery, radiosurgery/radiation therapy, and much more.
• Master new techniques with nearly 100 surgical videos online of intraoperative procedures including endoscopic techniques for spine and peripheral nerve surgery, the surgical resection for spinal cord hemangiomas, the resection of a giant AVM; and the radiosurgical and interventional therapy for vascular lesions and tumors.
• Confidently perform surgical techniques with access to full-color anatomic and surgical line drawings in this totally revised illustration program.
• Get fresh perspectives from new section editors and authors who are all respected international authorities in their respective neurosurgery specialties.
• Conveniently search the complete text online, view all of the videos, follow links to PubMed, and download all images at www.expertconsult.com.
Youmans is "the" neurosurgical reference. It covers the entirety of the specialty and the editors and authors are unparalleled in their experience and expertise.

Karen L. Roos - Emergency Neurology
Published: 2012-03-08 | ISBN: 0387885846 | 406 pages

The most common problems for which patients present to the Emergency Department are neurological disorders, including stroke, syncope, back pain and headache. The etiology of the patient's symptoms may be life-threatening, that is, when headache is due to subarachnoid hemorrhage or meningitis, or life-altering, that is, when back pain or weakness is due to spinal cord compression, if not diagnosed and treated urgently. This is a comprehensive textbook of the disorders that are neurological emergencies, including their differential diagnosis, diagnosis and treatment. Designed for any practitioner who makes time-sensitive decisions, Emergency Neurology is an indispensable, one-stop resource to aid your clinical decision-making.


Volume 97: Handbook of Clinical Neurology Series (Editors: Aminoff, Boller and Swaab) by Giuseppi Nappi and Michael A. Moskowitz MD
English | ISBN: 0444521399 | edition 2010 | 797 pages

This volume in the Handbook of Clinical Neurology series includes chapters dealing with general aspects of headache (socioeconomic in particular), the contribution made by the biological sciences to furthering understanding of the pathophysiology of headache, and the managemnt of headache and related problems.

The main body of the book is devoted to primary and secondary headaches. The book ends with some chapters intended to clarify a series of controversial issues: pathogenetic (chronobiological, endocrinological and neuroimaging correlates), nosographic (ie migraine, vertigo and headache in children) and treatment-related (new advances).

Clinical Trials in Neurology: Design, Conduct, Analysis By Bernard Ravina MD MSCE, Jeffrey Cummings, Michael McDermott, R. Michael Poole
2012 | 386 Pages | ISBN: 0521762596

Translating laboratory discoveries into successful therapeutics can be difficult. Clinical Trials in Neurology aims to improve the efficiency of clinical trials and the development of interventions in order to enhance the development of new treatments for neurologic diseases. It introduces the reader to the key concepts underpinning trials in the neurosciences. This volume tackles the challenges of developing therapies for neurologic disorders from measurement of agents in the nervous system to the progression of clinical signs and symptoms through illustrating specific study designs and their applications to different therapeutic areas. Clinical Trials in Neurology covers key issues in Phase I, II and III clinical trials, as well as post-marketing safety surveillance. Topics addressed include regulatory and implementation issues, outcome measures and common problems in drug development. Written by a multidisciplinary team, this comprehensive guide is essential reading for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and clinical researchers in the pharmaceutical industry.

Minesh P. Mehta, Susan M. Chang
"Principles and Practice of Neuro-Oncology: A Multidisciplinary Approach"
2011 | ISBN-10: 1933864788 | 1048 pages

Neuro-oncologic (brain and spine) cancers account for 19,000 new cases and 13,000 deaths per year. The early and proper diagnosis of these virulent cancers is critical to patient outcomes and diagnosis and treatment strategies are continually evolving. The multidisciplinary team that manages these patients involves medical radiation oncology, neurosurgery, molecular biology, neuroimaging, nurses and therapists. Principles and Practices of Neuro-Oncology establishes a new gold standard in care through a comprehensive, multidisciplinary text covering all aspects of neuro-oncology. Six major sections cover all topics related to epidemiology and etiology, molecular biology, clinical features and supportive care, imaging, neuroanatomy and neurosurgery, medical oncology and targeted therapies, and radiation oncology for adult and pediatric cancers. Over a hundred expert contributors provide in-depth and discussions of the most current knowledge of pathophysiology and etiology of neuro-oncologic tumors and state of the art discussions of clinical management. Throughout the book a multidisciplinary approach to management is emphasized.

"Attention Deficit Hyperactivity Disorder in Children and Adolescents"

Somnath Banerjee
InTeOpP | 2013 | ISBN: 9535110866 9789535110866 | 325 pages

This book has tried to address some of the issues in Attention Deficit Hyperactivity Disorder (ADHD)

ADHD in children and adolescents is a neurodevelopmental disorder, which is recognized by the clinicians all over the world. ADHD is a clinical diagnosis based on reliable history, reports from home and school and a physical examination to rule out any other underlying medical conditions.
ADHD can cause low self-esteem in the child and impair quality of life for the child and the family. It is known that ADHD is a chronic illness and that clinicians needed to use chronic illness principles in treating it.
The last 10 years have seen an increase in the number of medications that have been approved for the treatment of ADHD.

Section 1 Introduction
1 ADHD Through Different Developmental Stages
2 Neurodevelopmental Pathways of Childhood ADHD into Adulthood: Maturational Lag, Deviation, or Both?
3 Difficulties in Recognizing ADHD in an Urban Population and Treatment Satisfaction with a Short and a Long Acting Stimulant
4 Is ADHD a Stress-Related Disorder? Why Meditation Can Help
Section 2 Role of Endocrine Hormones
5 The Potential Role of Neuroendocrine in Patients with Attention-Deficit/Hyperactivity Disorder
6 Dopamine and Glutamate Interactions in ADHD: Implications for the Future Neuropharmacology of ADHD
Section 3 Assessment and Diagnosis
7 Clinical Phenomena of ADHD
8 Review of Tools Used for Assessing Teachers' Level of Knowledge with Regards Attention Deficit Hyperactivity Disorder (ADHD)
Section 4 Drugs in ADHD
9 Effects of Methylphenidate in Children with Attention Deficit Hyperactivity Disorder: A Comparison of Behavioral Results and Event-Related Potentials
10 The Impact of Attention Deficit/Hyperactivity Disorder in African-Americans: Current Challenges Associated with Diagnosis and Treatment
Section 5 Outcome
11 Attention-Deficit/Hyperactivity Disorder (ADHD) as a Barrier to Learning and Development within the South African Context: The Perspective of Teachers
12 ADHD Children's Emotion Regulation in FACE© - Perspective (Facilitating Adjustment of Cognition and Emotion): Theory, Research and Practice
13 A Comparison Between Life Quality and Weight-Height Measurements of Patients. Under Stimulant and Non-Stimulant Treatment due to Attention-Deficit and Hyperactivity Disorder, and Healthy Population
Section 6 Ethical Issues
14 Ethical Concerns Raised by Neuroscience. Labeling, and Intervening in the Lives of Individuals with ADHD

"MRI in Epilepsy" ed. by Horst Urbach
Springer | 2013 | ISBN: 9783642251375 9783642251382 | 269 pages

This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. This is detailed guide to the use of MRI in epilepsy. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.

Clearly relates clinical information to imaging findings
Emphasis on high-resolution and functional MRI
Edited by an expert who has supervised MRI in one of the world’s largest epilepsy surgery centers for more than 10 years

The first part of the book presents background information on epilepsy and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed.
The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings.

MRI in Epilepsy
Part I Epilepsy Patients and How to Examine Them
1 Epileptic Seizures and Epilepsy
2 Classification of Epileptic Seizures
3 Localization of Focal Seizures
4 Epilepsy Syndromes
5 The Term “Epileptogenic Lesion" and How to Use it
6 What To Do After a First Seizure?
7 How to Perform MRI
8 MRI of Children
9 Functional MRI
10 The Wada Test
11 Magnetic Resonance Spectroscopy in Chronic Epilepsy
12 SPECT and PET
13 Morphometric MRI Analysis
14 Metallic Implants
Part II Epileptogenic Lesions
15 Hippocampal Sclerosis
16 Limbic Encephalitis
17 Epilepsy Associated Tumors and Tumor-Like Lesions
18 Malformations of Cortical Development
19 Neurocutaneous Diseases (Phakomatoses)
20 Trauma
21 Vascular Malformations
22 Ischemia
23 Infection and Inflammation
24 Rasmussen Encephalitis
25 Metabolic Disorders
26 Other Epilepsy-Associated Diseases and Differential Diagnoses
27 Postsurgical MRI

Steven L. Lewis, "Neurological Disorders Due to Systemic Disease"
2013 | ISBN-10: 144433557X | 304 pages

Edited by Steven L Lewis, MD, Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA How do you identify which neurologic syndromes occur due to systemic disease? Neurological problems commonly occur in the context of underlying systemic disease, and may even be the presenting symptom of a medical condition that has not yet been diagnosed. Consequently neurologists need to be aware when a neurological presentation might indicate an underlying systemic disorder. Neurologic al Disorders due to Systemic Disease provides the tools you need to make these connections. The unique neurologic presentation–based approach relates to the common clinical situations you encounter, including: Headache Stroke Movement disorders Neuromuscular disorders Encephalopathies, seizures, myelopathies, neuro–ophthalmologic and neuro–otologic disorders, sleep disorders, and others Major categories of systemic illness are explored for each presentation to guide you towards a likely cause. These include: Endocrine, electrolyte, and metabolic disorders Systemic autoimmune disorders Organ dysfunction and failure, and critical medical illness Systemic cancer and paraneoplastic disorders Systemic infectious disease Complications due to drugs and alcohol Vitamin and mineral deficiencies Written by a leading cast of experts, with a practical approach including ‘things to remember’ for each presentation, Neurologic al Disorders due to Systemic Disease should be on every neurologist’s desk.

Abdul Qayyum Rana and John Anthony Morren, "Neurological Emergencies in Clinical Practice"
English | ISBN: 1447151909 | 2013 | 150 pages

Neurological Emergencies in Clinical Practice discusses neurological emergencies in a stepwise fashion including stabilizing the patient, identifying the cause, and treating the underlying cause. It is useful in several settings including the emergency room, hospital in-patient service as well as the intensive care unit.

Neurological Emergencies in Clinical Practice has a wide appeal and relevance to disciplines including neurology, emergency medicine, critical care medicine, internal medicine and family medicine. Medical students and residents may use this convenient, pocket-sized book to prepare for and succeed in their training examinations and it is also useful for other house staff and practicing physicians.

Joseph J. Volpe - Neurology of the Newborn (5th edition)
Published: 2008-05-13 | ISBN: 1416039953 | 1120 pages

The 5th edition of this indispensable resource captures the latest insights in neonatal neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has completely revised his masterwork from cover to cover, describing everything from the most up-to-the-minute discoveries in genetics through the latest advances in the diagnosis and management of neurologic disorders. He delivers all the clinical guidance you need to provide today's most effective care for neonates with neurological conditions.
Provides comprehensive coverage of neonatal neurology, solely written by the field's founding expert, Dr. Joseph Volpe - for a masterful, cohesive source of answers to any question that arises in your practice.
Focuses on clinical evaluation and management, while also examining the many scientific and technological advances that are revolutionizing neonatal neurology.
Organizes disease-focused chapters by affected body region for ease of reference.
Offers comprehensive updates from cover to cover to reflect all of the latest scientific and clinical knowledge, from our most current understanding of the genetic underpinnings of neurologic disease, through the most recent neuroimaging advances . . . state-of-the-art guidelines for evaluation, diagnosis, and prognosis . . . and the newest management approaches for every type of neonatal neuropathology.
Features a wealth of new, high-quality images that capture the many advances in neonatal neuroimaging, including numerous MR images.

Practical Handbook of Neurosurgery: From Leading Neurosurgeons, 3 Volume Set
Springer | 2009 | ISBN: 3211848193 | 1695 pages

The book invites the reader to an exciting journey through the vast fields of neurosurgery, accompanied by a large panel of leading neurosurgeons.

Ying Mao, ‎Hua Feng, ‎John H Zhang - Early Brain Injury or Cerebral Vasospasm: Volume 1: Pathophysiology
Published: 2010-12-06 | ISBN: 3709103525 | 264 pages

More than 40 articles provide an extensive coverage of clinical and basic science advances over the last three years of research on subarachnoid hemorrhage-induced brain injuries. Early brain injury, the new frontier of subarachnoid hemorrhage research, which may be a key contributor to the high mortality and morbidity, promotes collaborative efforts from neurosurgery, neurology, neuro-ICU into other interrelated fields and basic neurosciences. For the first time, subarachnoid hemorrhage research is almost equally divided by early brain injury and cerebral vasospasm, mechanistic investigations and therapeutic approaches, demonstrating a translational feature of the future direction.

Scott D. Z. Eggers, David S. Zee - Vertigo and Imbalance: Clinical Neurophysiology of the Vestibular System
Published: 2009-12-04 | ISBN: 0444529128 | 575 pages

Clinical neurophysiology encompasses the application of a wide variety of electrophysiologic methods to the analysis and recording of normal function, as well as to the diagnosis and treatment of diseases involving the central nervous system, peripheral nervous system, autonomic nervous system and muscles.

David J. Slutsky, ‎Vincent R. Hentz - Peripheral Nerve Surgery: Practical Applications in the Upper Extremity
Published: 2006-05-26 | ISBN: 0443066671 | 416 pages

This practical and comprehensive book provides you with today's best knowledge on the treatment of nerve injuries from the brachial plexus to the fingertip. Pioneers in peripheral nerve surgery from across North America and Europe offer you tips, pearls, and technical points gleaned from their decades of experience. They provide detailed discussions of standard techniques for nerve repair and grafting with the aid of electrodiagnostic techniques for fascicular matching, as well as new areas of end-to-side nerve repair, nerve transfers, and nerve conduits.
Lists the indications and specific instances in which nerve transfers may be used in place of tendon transfers for previously unrepairable nerve injuries.
Discusses the use of standard as well as new techniques of nerve reconstruction for the management of nerve injury for finger replantation or toe transfers.
Examines the treatment of chronic pain with the use of autogenous vein wrapping as a barrier to fibrous ingrowth.
Incorporates office-based studies and intraoperative nerve monitoring techniques so you can better interpret the electrodiagnostic test results for enhanced decision making in the treatment of nerve injuries.
Presents all clinically oriented chapters in a standardized format to include indications · a brief review of the literature · step-by-step surgical instructions · and results emphasizing the authors' own methods and experiences.
Provides expert coverage on how to section the nerve, which graft to use, and how to perform a matched fascicular repair.
Explores the use of two different, commercially available synthetic conduits.
Covers the indications, results, and technical points of neurotization for otherwise unsalvageable nerve avulsions.

Hyperkinetic Movement Disorders, with Desktop Edition: Differential Diagnosis and Treatment by Alberto Albanese and Joseph Jankovic
English | 2012 | ISBN: 1444333526 | 402 pages

Hyperkinetic movement disorders comprise a range of diseases characterized by unwanted and uncontrollable, or poorly controllable, involuntary movements. The phenomenology of these disorders is quite variable encompassing chorea, tremor, dystonia, myoclonus, tics, other dyskinesias, jerks and shakes.

Discerning the underlying condition can be very difficult given the range and variability of symptoms. But recognizing the phenomenology and understanding the pathophysiology are essential to ensure appropriate treatment.

Hyperkinetic Movement Disorders provides a clinical pathway for effective diagnosis and management of these disorders. The stellar international cast of authors distils the evidence so you can apply it into your practice. The judicious use of

• diagnostic criteria
• algorithms
• rating scales
• management guidelines
Provides a robust framework for clear patient management. Throughout the text, QR codes* provide smartphone access to case-study videos of hyperkinetic symptoms.
Purchase includes an enhanced Wiley Desktop Edition.* This is an interactive digital version featuring:
• all text and images in fully searchable form
• integrated videos of presentations
View a sample video: www.wiley.com/go/albanese
• highlighting and note taking facilities
• book marking
• linking to additional references
Hyperkinetic Movement Disorders provides you with the essential visual and practical tools you need to effectively diagnose and treat your patients.
*Full instructions for using QR codes and for downloading your digital Wiley DeskTop Edition are inside the book.

Andrei V. Alexandrov, "Neurovascular Examination: The Rapid Evaluation of Stroke Patients Using Ultrasound Waveform Interpretation"
English | ISBN: 1405185309 | 2013 | 216 pages

The use of neurovascular ultrasound is of increasing importance in neurological practice, both for radiologists and increasingly by neurologists themselves. Written by the world’s most renowned expert, this book explains ultrasound examination of a stroke patient scanning protocols interpretation of the results Case examples (with a standard template presentation correlating presentation to waveform output) reinforce the book′s practical nature. Illustrated with photos of the tests, explanations, and with actual waveforms, images, and result interpretation, and enhanced with ′pearls′ and ′avoiding pitfalls′ features, it is a practical reference for those learning ultrasound as well as those using ultrasound in their practices.
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